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Moreover, these enzymes can easily change their favorite substrate during evolution, as illustrated by studies showing that the replacement of one single precise residue in the CT sequence of one acyl-CoA carboxylase is enough to shift its substrate specificity [ 33, 34].
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Openarray technique will allow to analyze, in an unbiased way, the entire miRNome in one single reaction and will produce very precise and accurate data.
Information from one single molecular marker does not necessarily yield a precise reconstruction of evolutionary processes, but as indicated by many phylogenies constructed from other genes such as those encoding polymerases, ATPase subunits, elongation factors, and ribosomal proteins.
"The precise instructions to our armed forces are not to move one single soldier toward the border," said Juan Manuel Santos, Colombia's defense minister.
Archard (2006) notes that, for some writers, one cannot capture the early years of an individual's life within a single precise notion.
The representatives from Northern and Southern Sudan were very precise in their choice of language when they explained that they were both "from one single country, for now".
One single person.
Not one single question.
In one single night.
"One single proof".
Not one single horse.
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