Sentence examples for one serious problem is from inspiring English sources

One serious problem is that the TPP is not likely to include rules on currency, which is leading lawmakers from both parties to consider opposing the agreement.

One serious problem is how Greek officials could print new currency, a process that would take weeks or months, without word leaking out and provoking a bank run.

One serious problem is that contracts between the property managers and the "guardians" do not mention the word "tenant" at all.

One serious problem is that the injection is performed under OM, which has an imaging resolution limitation (approximately 200 nm); therefore, it makes challenges to the image processing.

One serious problem is the fact that due to the process of decomposition, contrast agents used for vessel visualization in the living cannot be used in cadavers.

But I think the more serious problem is the one you discuss toward the end of your column: Should not The Times tell readers that the Manhattan Institute is a conservative think tank (and the same for liberal think tanks, of course)?

Labour's serious problem is that no one will ever be able to prove whether what they did worked: if the recession is less deep, were these debts really necessary?

But there's one serious problem: It's never very funny, nor is the music particularly memorable.

One of the serious problems is the Sn inclusion (precipitates) formation during GeSn layer growth [10, 11].

However, Mr X faced one serious problem: there were no operational coal mines in the possession of the newly established company.

One of the most serious problems is the high noise level augmented by hard flooring and bare table tops.