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"one reason might be" is correct and usable in written English.
You can use it when making an argument by suggesting a possible explanation or underlying cause for something. For example: "One reason might be that the company failed to invest in new technology."
Exact(60)
One reason might be that down on the main floor of the show, denial had been in full force.
One reason might be lack of knowledge on their tumor-specific mechanism of action.
One reason might be the challenges in depositing a monolayer of metal nanoparticles on a surface with sufficient interparticle distances.
One reason might be a lack of investment.
One reason might be that the investors have no better place to turn.
One reason might be the well-known difficulty of forcing teen-agers to do anything.
One reason might be that there is so little talking in the film.
One reason might be found in the nature of Japanese religion.
One reason might be improved play by quarterbacks late in the game.
One reason might be that they think the added expense is too high.
One reason might be that investigators do not think many of the results from previous studies apply to theirs.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com