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We calculated the proportion of cells with more than one place field per track to be about 12% on the novel arm in the contiguous condition in control mice (Dragoi and Tonegawa, Nature 2011).
If each cell had at most one place field, then the two methods would be equivalent.
The megamap model flexibly recombines place cells to extend standard attractor network models of place cells, in which the majority of cells have one place field, to larger environments in which place cells have been shown experimentally to have multiple, irregularly spaced place fields [24 26].
The Hebbian weights are set as the sum of tuning curves, W_{jk} = W_{kj} = sum_{m=1}^{M_{j}} sum_{n=1}^{M_{k}} w_{mathrm{tune}}bigl(| textbf{c}_{jm}-textbf{c}_{kn}|bigr), where each cell j has the preferred locations ({textbf{c}_{jm}} _{m=1}^{M_{j}}), and (w_{mathrm{tune}}) is the weight profile determined by computing the optimal weights when each cell has exactly one place field.
The slower bump of activity acts as an envelope for the traveling wave, limiting its spatial extent to one place field.
For units displaying more than one place field, the place field size was computed as the sum of the existing fields.
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Currently, at least two predictive mechanisms related to evaluating future paths towards valuable goals in rats are known: one related to temporal encoding, where cells encoding future locations are activated along with current ones on place fields, and another with sharp-wave-ripple effects.
As phase locking is increased the path length increases asymptotically towards our analytical result, which is the distance traveled by the rat plus one full place field.
We computed the proportion of spikes representing proximal locations and assessed whether the proportion differed significantly (using a binomial test) from what one would expect based on the place field distribution of the cued arm.
Of concern to Clarke will be one notable absence from the WGC in the form of Ian Poulter who fell one place outside the field's 66-place qualifying cut off.
Big social groups that stayed in one place, working their fields, flourished at the expense of smaller, less sedentary ones.
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