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One of the pathway steps is uniquely catalyzed by RRM2B, given that the other genes associated to this reaction (RRM1 and RRM2) are not expressed in ccRCC.
We further investigated one of the pathway clusters found using PubMatrix.
The nomination can be for any one of the Pathway Program Award types: Initiator, Accelerator or Visionary.
A reaction can be found by entering one or more metabolites or by selecting the pathway it is part of in one of the pathway databases.
In contrast, using the gene lists from the 10 simulated datasets, nine of the 10 pathway analyses yielded no significant pathways enriched for at the same p-value with one of the pathway analyses yielding one significant pathway.
Although investigations on D. discoideum have been limited to establishing the intracellular location for FDPS, they would imply that current understanding of the overall organization of the mevalonate pathway, and of the cellular events leading to inhibition of one of the pathway enzymes by the NBPs, is incomplete.
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The foregoing experiment suggested that 22L and RML prions were taken up predominately by clathrin- and caveolin-independent pathways, or that the two strains can be internalized by either one of the pathways, dependent on accessibility.
Inflammatory responses may be one of the pathways involved in these effects on adult health.
Wilner is one of the Pathways to Science participants who have gone on to study science in college.
ROS-activated α-SMA is considered to be one of the pathways of aberrant proliferation.
One of the pathways repairs DNA double-strand breaks through a process called homologous recombination2 (HR).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com