Sentence examples for one major issue from inspiring English sources

Arianna broke with O'Donnell, though, on one major issue.

At least on one major issue, he already has a fully formed opinion.

One major issue focused on the advances in sensitivity and specificity but also on compatibility, accessibility, and affordability.

One major issue with this book, however, rests on how Hurd presents this information.

Disposal is one major issue.

I have one major issue with it.

One major issue remains – allocation of job opportunities.

"One major issue was: What was the right pricing?

The debate usually boils down to one major issue: creativity.

One major issue is who should staff the programs.

One major issue is carbon dioxide, or CO2.