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Discover LudwigThe phrase "one main reason" is correct and usable in written English.
You can use it whenever you are introducing a main argument or point you are making. For example: "One main reason why I think this is a good idea is that it will save time and money."
Exact(59)
Patrick is far down on this list for one main reason: People don't think he'll run.
One main reason is that Mr Brown came to rely on fickle revenues from overheated property markets and frothy finance.
One main reason is uncertainty.
They ended up here for one main reason.
One main reason for this is that data is usually originated from disparate sources.
There is one main reason why the money position may not balance in this way.
One main reason for the war is the poor economy," she said.
That may be one main reason why they were attacked, he says.
One main reason: There are not enough faculty to teach incoming nursing students.
They have been able to do so for one main reason: money is available.
And that's one main reason our soldiers are still dying in Iraq.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com