The phrase "one main explanation" is correct and usable in written English.
You can use it when referring to a single primary reason or justification for something. For example: "One main explanation for the rise in violent crime is the lack of job opportunities in the area."
One main explanation on tumor cell resistance to paclitaxel is the overexpression of P-glycoprotein (P-gp, MDR-1), which works as a drug efflux pump.
One main explanation is that the German system of wage setting is shaped by collective contracts and an attachment of wages to jobs rather than to individual abilities.
The researchers concluded that one main explanation is that upper management "is concerned that large-scale discipline would implicitly acknowledge widespread wrongdoing and lack of oversight".
One main explanation lies in the sustained level of foetal haemoglobin (HbF) and F cells during this period (Maier-Redelsperger et al., 1994) preventing HbS polymerisation (Nagel et al., 1979).
However, the result showed that one main explanation to a low motivation score was when the student had a bad life-situation such as a stressful situation at home.
One of main explanations relies on the use of psychoactive substances (alcohol, illegal and medicinal drugs), which are known to be major risk factors of road accidents, and whose consumption is almost universally more common among younger drivers.
One of main explanations relies on the use of psychoactive substances (alcohol, illegal and medicinal drugs), which are known to be major risk factors of road accidents [ 6- 12], and whose consumption is almost universally more common among younger drivers [ 13- 16].
One of the main explanation may be due to differences in cohort composition.
One main one and one backup.
But one suspects that the main explanation for fund managers' near-silence is Shell's status as a global titan whose board cannot be embarrassed into seeking a last-minute renegotiation of terms.
In the literature on partners' retirement decisions, one of the main explanations for joint retirement is leisure complementarities.
