Sentence examples for one main difficulty from inspiring English sources

One main difficulty of block-based approaches is how to efficiently identify the homogeneous blocks.

In order to obtain those results, we have to overcome one main difficulty: the minimization problem ( I q ) is given in the unbounded domain ℝ which results in the loss of compactness.

One main difficulty is to assess their interactions with components of the intestinal immune system, especially the DCs, a key player in mucosal immunity.

One main difficulty in addressing this issue consists in instructing a new task to sleeping subjects, arguably because prefrontal regions dealing with executive functions are then particularly suppressed in comparison to other cortical regions [ 8, 9].

One main difficulty is that current experimental models are not able to follow the progression of the disease, which could allow researchers to distinguish causative mechanisms from secondary effects, thus gaining more insights into the molecular basis of FRDA.

Papers on motivation to change in AN allowed a better understanding of denial of illness although one main difficulty encountered in this field of research is to understand patients' authentic degree of motivation to recover since there is often a difference between what patients do and say [ 100].

One of main difficulties for this target is to maintain it at high temperature (more than 2000 °C) during 3 months.

One main issue was difficulty in operationalization.

One of the main difficulties on developing mixed-mode behavioral circuits is on finding a tradeoff between speed, accuracy, and convergence.

The main difficulty one faces when developing numerical schemes for Equations 22 and 24 is that they are non-local.

This may have been one contributor to the main difficulty the students had when using the tool, namely interruption by the clinician to whom they were talking.