Such an opinion is a reasonable one since total lifetime exposure to estrogens is one of the primary determinants in the development of this type of hormone sensitive cancer, and consequently many organochlorine pesticides, among a host of other xenobiotics, have been shown to act as estrogenic agents.
However, positive skin prick test to Dermatophagoides farinae was associated with one quartile increase of lifetime exposure to traffic pollutants.
Inhalation unit risk estimates consider the individual lifetime excess risk resulting from chronic lifetime exposure to one unit of pollutant concentration.
Inhalation unit risk estimates are defined as the individual lifetime excess risk due to a chronic lifetime exposure to one unit of pollutant concentration (U.S. EPA 2003).
It may be that cumulative lifetime exposure to one or more metals, not adequately captured by blood levels measured cross-sectionally in our study, are responsible for adverse health effects of exposure.
We relied on this metric of lifetime exposure as our primary exposure metric.
Because our focus was on lifetime ETS exposure, there is no other available ETS exposure methodology.
In our sample, lifetime exposure to at least one of the nine life events enquired about was almost ubiquitous (89%, n = 1478) and 25% (n = 422) reported exposure to at least one event in the preceding year.
Prevalence (standard error) of exposure to at least one lifetime PTE was 73.8% (1.15) in the total sample, while the average person exposed to any lifetime PTE reported an average of 4.3 occurrences, for a total of approximately 13,700 lifetime PTEs experienced by the 4,315 SASH respondents (Table 1).
Thus, blood lipid concentrations, blood pressure, smoking habits and other CV risks estimated at one point in time, may not accurately represent lifetime exposure.
