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In these studies, more than half (52 66%) of all chest CTs showed at least one incidental finding.
By synthesising all the published data on incidental brain findings and adding unpublished data where possible, we increased the precision of existing estimates of their prevalence across the whole age range and used a novel metric of the number needed to scan to detect one incidental finding (fig 1).
As a second example of the lack of concordance, one incidental finding in our study was the perception that "zero" women (perceived as true by clinical officers) used traditional birth attendants (TBA), versus "half of women" (perceived as true by community health workers and couples) frequented births with TBA.
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A little over one month ago, on March 21, the American College of Medical Genetics and Genomics (ACMG) announced a set of recommendations on incidental findings in clinical sequencing.
ACMG recommendations on incidental findings are flawed scientifically and ethically.
Pulmonary nodules were the most frequently encountered incidental finding.
The number of asymptomatic people needed to scan to detect one incidental brain finding, or number needed to scan, was the reciprocal of the prevalence estimate.
In one review, incidental findings appeared on 24% of a mixed collection of radiologic cases (Lumbreras, Donat, & Hernández-Aguado, 2010).
Three women were diagnosed following an incidental finding: one during an emergency hysterectomy for post-partum haemorrhage, one during emergency Caesarean section and one after presenting to a sexual health clinic for a sexually transmitted infection screen.
The Gleason 6 tumor was an incidental finding, one sample with 2% infiltrated.
Another point which should be kept in mind when interpreting our results is that in Germany there are standardized physical examinations for children (which the statutory health insurer pays for) and scoliosis might be identified and be coded as an incidental finding during one of these examinations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com