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One frequent objective of the projects that use NGS sequences is to look for sequence variation (SNPs and small indels).
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In addition to locating probes that show copy number changes, the identification of common or recurrent regions of alteration is one frequent study objective: the regions more likely to harbor disease-critical genes are those that are recurrent or common among samples (Diskin et al., 2006; Pinkel and Albertson, 2005).
One of the challenges of the CBME model is the organization of frequent, objective assessments, requiring considerable faculty involvement and resources [ 22– 22].
One frequent visitor is Reggie Holland, 53, who lives nearby.
One frequent complaint involves Greenpoint's relative inconvenience to Manhattan.
One frequent approach is to place plugs of compliant material into the midsole of the shoe.
In addition, anthropometrics and waist circumference were the most frequent objective indicators.
Identifying genes that are differentially expressed among groups of diseased tissue samples is a frequent objective of gene expression profiling.
Is one more objective?
Each definition actually involves one performance objective.
Our number one objective had been achieved.
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