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Nevertheless, the occurrence of more than one AS case in individual flocks has been reported [ 4, 11- 13].
Under these conditions, the cumulative probability over 10 years to detect at least one AS case out of 200 animals tested for TSEs would be 10%.
One AS case was detected in an Irish flock with a CS index case however this case was identified via clinical surveillance testing (histopathology and immunohistochemistry) rather than group test analyses and was excluded for this reason from data analyses.
For each country that was capable of detecting AS, but which did not detect any AS case, the probability of detecting at least one AS case among all tested animals was estimated for the situation where the within country ASPE was set to equal the calculated overall prevalence of atypical scrapie in the responding countries.
For each year and country in which at least one AS case was detected and more than 500 animals tested, the ASPE in healthy slaughtered animals varied from 0.1‰ [0.0;0.3] in Switzerland in 2004 to 1.4‰ [0.8;2.3] in Great Britain in 2005 and the ASPE in fallen stock varied from 0.3‰ [0.0;1.5] in Norway in 2005 to 2.5‰ [1.0;5.2] in Great Britain in 2003.
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In Ireland one additional AS case was found among a limited number of examined animals, however this single research flock was investigated with an alternative control strategy and one additional AS case was also found in an AS positive flock prior to the period covered by data collected [ 13].
The target RMS d misfit was set at one as in Case I.
Two of these patients were classified as coronary vasospasm and one as a case of perimyocarditis.
Every site employs Learning Advocates who work with families on a one-to-one basis, serving as case managers, tutors, and friends.
The necessity of oversampling can be illustrated for one dimension case as follows.
"I do not think of it as one Google case but literally as different investigations and different cases," she said.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com