These modeling results are consistent with an assumption that each STI case treated would prevent, on average, one additional case of that STI in the population.
The number needed to treat (NNT) then is 1/.2 = 5, implying that for every 5 cases with SS & IFI, on average, one additional case will die as compared with those having SS & no IFI.
The NNT to detect one LTBI case was 30 using TST as a single test and 21.4 using QFT-GIT as a single test; the NNT with QFT as an add-on test to detect one additional case was 36.2.
Five samples were stored in fixative for over 10 years, two of which were also flash frozen and sectioned on a freezing microtome, and one additional case was fixed for 3 years and sectioned on a freezing microtome.
One additional case was suspected based on lesions observed on histopathology, but the liver tested microcystin-negative, perhaps due to near-total loss of hepatocyte mass in the liver of this animal.
In addition, IGRA may detect one additional case of LTBI out of 56 patients that would otherwise be missed using solely TST.
Had we used a more conservative definition (e.g. ≥3 days, based on the median incubation period), one additional case would have been reclassified, representing a secondary attack proportion of 7.2%.
One additional case study was completed on a TI working with long-distance truckers.
One of these cases also showed trisomy chromosome 7. Monosomy of chromosome 8 was seen in a further two cases (17%), and a partial loss on chromosome 14 was observed in one additional case.
The results of 56 surgeons who performed 710 procedures from 1994 to 2000 revealed no statistically significant relationship between surgeon volume and mortality based on the analysis of an increase of one additional case per year (p = 0.49).
When treating hospital volume as a continuous variable an increase of one additional case per year showed no statistically significant effect on the mortality rate (p = 0.38).
