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As our data are prognostic and not mechanistic we cannot conclude on which pathways are operative in non-GIST STSs expressing VEGFs and VEGFRs.
However in our hands with the H441 cell line where with no CFTR present we found that there was no significant change in NF-κB activity when treated with the inhibitor, however when CFTR was present there was a significant increase in NF-κB activity, suggesting that the effects of the inhibitor may differ between cell lines, depending on which pathways remain intact (compare figure 3C with 1D).
Therefore, choices have to be made on which pathways will be drawn well in priority.
The overall response of neurons to stimuli, however, depends on which pathways are predominantly regulated.
To gain an insight on which pathways are modulated during S. cerevisiae exposure to propolis, we determined its transcriptional profiling.
Careful, respectful genetic study of these genetically unique populations may provide information on which pathways in human biochemistry and physiology promote resistance to human rabies.
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Addtionally, one can gain inference on which pathway an enzyme belongs to with the knowledge of its proper sucellular localization and basic function in hand [8].
This is because Skn7p is a modular transcription factor that can affect different sets of genes through distinct domains, depending on which pathway activates it (Alberts et al. 1998; He et al. 2009).
The decision on which pathway of transmission a model should be based, has far-reaching implications for the modelling strategy: aerosol transmission would be best represented by dynamic affiliation networks (individuals contaminate places; cf. [ 30]) and the transmission risk depends vastly on ventilation conditions and less on social interaction [ 31].
Each has advantages and disadvantages that you'll need to explore before reaching your final decision on which pathway to pursue.
Thus this KEGG analysis is technically preliminary; therefore only a detailed examination of individual pathways will allow on to decide which pathways are actual active.
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