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Understanding the mechanism of oligonucleotide (ON) uptake and cellular distribution is important for rational design of ON-based therapeutic strategies.
Further details on uptake will be published from next week.
What the neighbours are doing also had the strongest influence on uptake of the new drugs Nesta studied.
New safety technologies can take a decade to reach the population en masse, because they rely on uptake by manufacturers and then a gradual replacement of older car stocks.
That could be a ways off, depending on uptake.
The effect of pore size on uptake was also evaluated.
Understand that the need for customer education can also have an impact on uptake as well: It's crucial to convey products' and services' core value proposition at a glance, and make supporting features simple to comprehend and access.
JNK inhibition had no effect on uptake of any strain or form of S. aureus.
Rac1, Rho or Arf6 depletion did not have major effects on uptake of either probe (Figure 6A).
We focused on ERK, as inhibition of this pathway had much greater effects than p38 inhibition on uptake and glycolysis.
We began to assess the effect of mutations of these 3 residues on uptake activity, whole cell, and surface expression.
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