To routinely assess the effectiveness of ART at HIV treatment clinics and to minimize preventable HIV drug resistance (HIVDR), WHO recommends using available site-based data from medical and pharmacy records, e.g. on-time adherence to monthly ART drug pick-up and clinic appointment-keeping [9], [10], as an early warning indicator (EWI) of inconsistent drug exposure.
Our findings were consistent with a previous study from two districts in northern Vietnam, which reported 24.9% non-adherence and 29.0% not-on-time-adherence (7).
The prevalence of one-month suboptimal adherence measured by VAS was 24.9% (153/615), while the prevalence of 4-day not-on-time-adherence using the AACTG instrument was 29% (179/615).
Descriptive analyses were done on baseline patient characteristics and on outcomes for wearing time, adherence, and step activity.
To the best of our knowledge, there is only one published study on long-time adherence over 4 years of intradialytic training 44 with initially 24 patients who were on average 53 years old.
Therefore UNICEF ought to move with speed to ensure the activities planned for the districts lagging behind are implemented on time, with strict adherence to quality and quantity design specifications.
Patients like Tina are so commonplace at Family Medical that the clinic employs a full-time "adherence counselor," Ed Robinson.
According to WHO [9], [10], monitoring the extent to which ART sites function through EWIs such as adherence to on-time drug refills is of high priority in order to minimize preventable HIVDR.
There were no significant differences between groups, but trends were observed for the MI-CBT/mDOT group to have greater 12 week on-time and worse 48 week adherence than the SC group.
It would be curious to know the reasons for not getting a full 100% daily compliance adherence, when every break and lunch I have taken has been taken on-time, without delay, and within the limits imposed.
