Sentence examples for on the initial hit from inspiring English sources

None of Sears's tired Illinois stores were on the initial hit list of 79.

By examining the substituents on the initial hit 14 with 4-hydroxyphenyl 23 and 3-methoxyphenyl 24 separately, 4-hydroxy was found to be responsible for retention of HsCDK2 activity, while monosubstituted 3-methoxy was inactive against HsCDK2.

Optimization of the initial hit compounds revealed inhibitor 39.

But that was for the initial hit off the post.

The initial hit expansion focused on optimising the substituents around the thiazolidinone ring.

Our program iterates through the initial hit list, performing a BLASTn search on the hit identifying overlapping traces based upon an e-value cut off.

In the first case the initial hit should provide a proliferation boost, in the second the hit should bestow self-renewal on the proliferating progenitor [ 108].

The initial hit, MW069a, was obtained by alternative placement of the pyridine substituent on the pyridazine core of a safe, brain penetrant experimental therapeutic, MW189.

How many steps can eventually be individualized may depend on how many clones are initially expanded, on the level of genetic instability that results from the initial hits, and on the impact of the mutations on self-renewal, differentiation and proliferation.

Development of quality leads using hit confirmation and hit-to-lead approaches present their own challenges, depending on the hit discovery method used to identify the initial hits.

The initial hits from the electronic databases were exported to EndNote and checked for duplication.