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Typically, studies on reprogramming focus specifically on the differentiated cells undergoing reprogramming to stem cells9 while the cellular state of the cells that remain unchanged are not closely examined.
At day 37, cell cycle analysis performed on the differentiated osteoblast population showed that cells in S phase were about 39% and that all cells were still euploid (Figure 2d).
The aim of this study was to examine the effect of three-dimensional (3D) architecture on the differentiated phenotype of human smooth muscle cells derived from the stroma of the lower urinary tract.
These early trials relied on the differentiated cells (i.e., chondrocytes making more chondrocytes), porous scaffolds that provided a substrate for cell differentiation from adult stem cells (osteoconductive or osteoinductive scaffolds), or induction of unknown tissue differentiation events.
It is concluded that by bringing a focus on the differentiated socio-spatial contexts of particular places, it could serve to trigger much wider political debate around the spatial challenges associated with the roll-out of onshore wind energy networks in highly congested and contested spaces, and the possibilities for alternative energy pathways.
Specific binding proteins for the chemoattractants were identified by covalent affinity labeling on the differentiated U937 cells as well as on normal human monocytes.
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Subsequently, we depolarized hMSCs after pre-differentiating them toward osteoblasts or adipocytes to investigate the effects of depolarization on maintenance of the differentiated phenotype.
The main tenet of functionalism is that scientific analysis and explanation must focus on the functional integration of the differentiated component parts of a given structure or whole.
Here we show that H3K14ac, H3K4me3 and H3K4me1 each exhibit a characteristic distribution on nanochromosomes in the differentiated macronucleus.
To investigate the effect of PAQG on lipid metabolism in adipocytes, the differentiated adipocytes on day 5 7 were treated with PAQG at various concentrations (Fig. 3a up panel).
If heterogeneous differentiation was found in the obtained HCC tissue, differentiation grade was classified based on the lowest differentiated grade.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com