Scenarios 4 6 are based on the same three villages but use a 1.5% water buffalo S. japonicum prevalence based on that observed in Samar, the Philippines [32] [34], so as to simulate transmission under conditions of low S. japonicum prevalence in water buffaloes.
Endemic scenarios 4 6 used the same parameters as scenarios 1 3, respectively, except for the water buffalo S. japonicum prevalence, which was based on that observed in Samar, the Philippines [32] [34], so as to simulate transmission under conditions of very low (1.5%) S. japonicum prevalence.
This enabled us to estimate levels of variation in the infected material sample based on that observed in the replicated haustoria samples.
It may be argued that the possible discordant HER2 status between paired dysplasia and GC should indicate that extrapolation of HER2 status of invasive carcinoma based on that observed in dysplasia is not reliable.
The population structure was based on that observed in the real geographical pattern with I = 147 areas, whereas the expected counts were derived using the overall age-sex specific rates for the most frequent (hip fracture) and the least frequent (lower extremity amputation) procedure.
