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These secretions are carried by the blood to distant sites (target organs), where they bind to specific receptors on target cells and act to regulate specific chemical reactions.
Three kringle domains (K1, K2 and K4) displayed agonistic activity on target cells.
The HIV-1 transactivating factor (Tat) acts as an extracellular cytokine on target cells, including endothelium.
IL-4 mediates its function by binding to receptors expressed on target cells such as T lymphocytes, and macrophages.
Targeting requires that a ligand on the nanoparticle surface interact with a specific membrane receptor on target cells.
A PLL coating on IONPs could lead to improved electrostatic binding on target cells and thus enhance cellular uptake.
Photodynamic therapy with 5-aminolevulinic acid (5-ALA-PDT) exerts cell type specific effects on target cells.
Finally, the probes were tested on target cells before they were used for mimicking preconception or preimplantation genetic diagnosis.
Both A and C induced peptide-specific, IFN-γ-secreting cytolytic CTLs upon antigen recognition on target cells.
We also examined the biological effects of an amino-terminal truncation mutant leukotoxin ΔLktA on target cells.
Antihistamines block the histamine release from mast cells and prevent histamines from binding with receptor sites on target cells.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com