For COPD drug approvals based on surrogates, a medical review for one drug (TUDORZA PRESSAIR) mentioned the limitations of using lung function and the importance of evaluating patient-centred outcomes such as COPD exacerbations.
With a candidate of Rubio's oratory skills and telegenic charm, supporters say they are confident the strategy is a winning one, and leaves the campaign less reliant on surrogates to deliver his message.
He relies heavily on surrogates, and tends to back into his attacks.
Mrs. Clinton and Mr. Obama were relying on surrogates to help carry their message ahead of the contests this week.
Mr. McCall was in California today to raise money, forcing him to rely on surrogates to stump for him.
The couple said that Mr. Giuliani could flood the airwaves with commercials, make limited appearances and lean on surrogates like Senator John McCain.
The Republicans have much smaller teams — about 70 in this county — and will rely more on surrogates, including nonlawyer poll workers.
Instead of putting the candidate on the trail, Mr. Romney's campaign has leaned more heavily on surrogates, television ads and interviews and Web videos to drive their message.
