Sentence examples for on strong rationale from inspiring English sources

The Centers for Disease Control report comprises three classes of evidence: recommended strategies are based on strong rationale and suggestive evidence, suggested strategies may be supported by suggestive clinical or epidemiologic studies, and no recommendations are given for practices for which insufficient evidence or consensus regarding efficacy exists.

Again, an approach based on a strong rationale, and some luck, led to the identification of activating mutations of the KIT gene in approximately 90% of gastrointestinal stromal tumours (GISTs); among KIT wild-type cases, 35% display activating mutations in PDGFRA.

On the one hand, there was a strong rationale for using DAA or corticosteroids in sepsis [12].

On this basis, a strong rationale existed for the use of bevacizumab, an anti-VEGF monoclonal antibody, for treatment of rMGs (recurrent malignant gliomas).

These observations, along with the ubiquitous yet selective expression of BCMA on MMCs, provide a strong rationale for the development of mAbs targeting BCMA.

Thus there is no strong rationale to support one method as being superior to another.

16, 17 Based on these findings there is a strong rationale for exploring the potential of macrophage-based therapeutics to improve outcomes after acute liver injury.

Moreover, the likelihood of mental health problems increases with the increase in number of unhealthy behaviors providing strong rationale to intervene on combined unhealthy lifestyle behaviors at the population level.

In this context, in-depth investigation on TKI chemosensitizing functions might provide a strong rationale for combining TKIs and conventional therapeutics in specific malignancies.

Despite the tremendous successes of current vaccines, infectious diseases still take a heavy toll on the global population, and that provides strong rationale for broadening our vaccine development repertoire.

This observation provides a strong rationale for continued focus on the contribution of both classes of protease inhibitors to OA pathogenesis.