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In this review, we critically evaluate previous attempts to use non-specific antioxidants as neuroprotectors and emphasize new approaches based on recent breakthroughs in understanding of enzymatic mechanisms of lipid peroxidation associated with specific death pathways, particularly apoptosis.
Stem cell research is currently one of the most active areas in molecular biology and biomedicine, based in part on recent breakthroughs in generating 'induced pluripotent stem cells' (iPS cells) from somatic cells like fibroblasts (reviewed in [ 48, 49]).
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Due to recent breakthroughs in the large-scale energy storage technology and lower prices, a power system auxiliary service market based on large-scale ESSs is developed.
Here we review the structural and molecular biology of curli biogenesis, with a focus on the recent breakthroughs in our understanding of subunit chaperoning and secretion.
In this review we focus on the recent breakthroughs about the supramolecular structure of NF-T3SS key subassemblies, highlighting analogies to the equivalent flagellar components, when appropriate.
Finally, a focus on electrowetting is made from historical phenomenon pointed out some decades ago on classical planar hydrophobic surfaces to recent breakthrough obtained on superhydrophobic surfaces.
Recent breakthroughs on our understanding of mucosal immune responses in teleost fish open up the potential of teleosts as animal research models for the study of human mucosal diseases.
Recent breakthroughs on induced pluripotent stem cells (iPSCs) have been considered as a milestone in science and medicine.
We then focus on the recent breakthrough work concerning the structural basis of the PD-1/PD-Ls interaction and how therapeutic antibodies, pembrolizumab targeting PD-1 and avelumab targeting PD-L1, compete with the binding of PD-1/PD-L1 to interrupt the PD-1/PD-L1 interaction.
Here, we will concentrate on technical aspects of the spin trapping/EPR technique, delineating recent breakthroughs, inherent limitations, and potential artifacts.
It has long been unclear how mitochondrial cristae are formed, and two recent breakthroughs have dramatically changed our view on this topic.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com