Sentence examples for on rate for from inspiring English sources

Indeed, with the helical structure of aS in the lipid-bound state being well established, preformation of helical structure at the N-terminus in aqueous solution will significantly increase the on rate for binding of aS to lipid, while not significantly affecting the off rate.

The constitutively expressed PP7-coat protein tagged with mCherry (PCP-mCherry) and MS2-coat protein tagged with GFP (MCP-GFP) bind with high affinity (the on rate for MCP is 0.54 μM–1s–1.

The avidity effect allows us to assume that the on-rate for RP bound to one monomer to bind an adjacent monomer on the same tetramer is very large, due to the increased local concentration (kon2, kon3 >> kon1 PPDK T, kon4 PPDK T).

While the force regulation of off-rate for dissociation of selectin ligand bonds has been extensively studied, much less is known about how transport impacts the on-rate for association of these bonds and their stability.

For very fast transients below the steady-state time constant, the on-rate for the indicator may not be fast enough and also binding of calcium to the indicator may be diffusion limited.

The on-rate for a diffusion-limited encounter between two proteins is in the range of 10 to 10 M−10−10

As a result, the on-rate for the second binding is very high (typical avidity effects show an on rate that is 100 times or more larger than the first binding rate [ 4, 22]).

Because the on-rate for this high-affinity binding interaction is fast, the slower on-rate of Sly1 binding to the SNARE core bundle would have been obscured by the high-affinity Sly1-N-peptide interaction in previously published experiments.

Although the on-rate for Chl b may be slower than that for Chl a, because binding may be impeded by a water molecule more strongly coordinated to the central Mg atom of Chl b, the greater Lewis acid strength of Chl b allows more stable bonds with the weaker ligands.

Using physically reasonable values for the on and off rates and the catalytic rates we show that a small increase in on-rate for Btk dimer formation leads to a dramatic increase in the rate of autophosphorylation, even though the concentration of Btk is two orders of magnitude below the value of the dissociation constant.

In looking at non-HIV antibody lineage affinity gains, fitting the same category of predominant off-rate improvements is a series of anti- 4-hydroxy-3-nitrophenyl)anti- 4-hydroxy-3-nitrophenylost manti- 4-hydroxy-3-nitrophenyl 5-fold improved off-ranti- 4-hydroxy-3-nitrophenylber, with anti- 4-hydroxy-3-nitrophenylpacetyle compantibodiesgawhere al., 2003).