Suggestions(4)
Exact(44)
Similarly, mouse mutants with an ON pathway defect [42] show increased susceptibility to FDM.
Figure 5 Effects of BRAF and MEK on pathway proteins.
fluorescens mixed culture, with lactate having a slight negative impact on pathway II utilization.
On pathway detail pages (Figure 2A), graphical diagrams of the pathways can be viewed at different levels of detail.
In this study, we systematically investigate ERK signalling pathway components and topological structures that determine their influences on pathway activity and targeted therapies.
In particular, we focused on ERK signalling to systematically investigate the influence of gene alterations, and pathway topological structure on pathway activity and drug sensitivity.
Similar(16)
The four-helix protein Im7 folds through an on-pathway intermediate at pH 7.0 and 10 °C.
Despite its apparent architectural simplicity, IκBα67-206 displays complex folding kinetics, with two sequential on-pathway high-energy intermediates.
Furthermore, we aimed to determine the ability of CEppt to inhibit on-pathway Aβ oligomer formation.
It was widely believed that these oligomers are intermediates along the fibril formation pathway (on-pathway).
Although seeding is suggestive of intermediates being 'on-pathway', the ability of 12 18 mers to seed fibril formation may indicate their structural similarity with the on-pathway fibrils.
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