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Based on our test submissions, we chose 1.0E-02 1.0E-02shold for Sas-threshold fornd little evidence for false positives with lower E-vasues.
We also thank anonymous reviewers for their constructive and valuable comments and suggestions on our previous submission.
[Editors' note: the author responses to the previous round of peer review follow.] Thank you for the very constructive comments on our previous submission.
Given the reviewers' comments on our original submission (reproduced above), we did not recognize that they were requesting that we examine the proportion of early 145K mutations that arose in SE Asia on the phylogeny.
"We are still in the process of preparing our submission on the away game and to be confronted with this now seems chaotic to say the least.
[Editors' note: the author responses to the first round of peer review follow.] Thank you for reviewing our submission "Limits on information transduction through regulation of signaling dynamics".
"In other places of spiritual encounter we more easily recognise the structures and symbols that encroach on our sense of submission or tolerance –- we can opt in or out, avoid lines of symbolism too potent or revel in something in which we feel excited, comforted, or infused.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com