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The ability to identify a panel of miRs as a biomarker rather than relying on one marker will increase the odds of successful treatment in a heterogeneous population of patients.
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Using markers of the HD chip that passed quality control (see below), four 15 K chips were simulated based on selection of one marker from each window of 29 subsequent markers, according to the UMD v3.1 assembly.
Using the combined datasets, we calculated a summary statistic for each pair of SNPs using the genotypes of one marker conditioned on another marker, and evaluated the significance of each result using a permutation test (10,000 permutations) (Table 2).
Nevertheless, we compared the electrophoresis patterns of the two cultivars of the 36 STS markers scattering on all the chromosomes with the result that the two cultivars share the same patterns except for one marker on chromosome 10 (Ichitani et al., unpublished results).
On average, one marker per 2.94 cM was found in the 'MxR_01' map.
This method can efficiently rediscover many entire biological systems, such as histidine biosynthesis genes, given a profile based on any one marker gene for the system.
Within the confidence interval of the QTL detected on LG3, one marker named f68558 was found to be located in the intron region of a transcription factor gene, PROP1 (Homeobox protein prophet of Pit-1) (Fig. 7 and Supplementary Table S1).
The SNP panel contained three markers on chromosomes 1, 2, 3, 4, 5, 6, 7, 8, 9, 10 and 12, two markers on chromosomes 11, 13, 14, 15, 16, 17, 18 and 19, and one marker on the X chromosome.
The locus detected in 2015 conditions involved only one marker on chromosome 12 at position 4423506.
One marker on chromosome 14 was associated with differences in fat yield, fat percentage, and a canonical production trait in two families.
These features were computed from the visual domain using four markers from the lips (for protrusion, opening and spreading) and one marker on the chin (for the jaw)[30].
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