Development in systems biology research has accelerated in recent years, and the reconstructions for molecular networks can provide a global view to enable in-depth investigation on numerous system properties in biology.
Other than birth weight, animal studies have shown effects of PFOS and PFOA on numerous organ systems, thyroid function, endocrine system, immune function, and congenital anomalies (Chang et al. 2008; Luebker et al. 2005b; Peden-Adams et al. 2007; Seacat et al. 2002; Thibodeaux et al. 2003).
Increasingly we are coming to understand that it is not enough to be a system leader, overseeing a single system of services for children and young people, rather we must be involved in shaping the numerous systems that impact on the lives of children and their families across the public sector.
Furthermore, numerous systems biology approaches based on gene expression data for in silico drug repositioning have been published [ 62, 63].
Given the impact of wheel-running behavior on numerous overlapping systems that influence behavior and physiology, this review outlines the need for careful design and interpretation of studies that utilize running wheels as a means for exercise or as a measurement of general physical activity.
These peptides have been demonstrated to have pleiotrophic effects on numerous cell systems including anti-apoptotic actions in heart and the regulation of skeletal osteoclast differentiation and resorption, acting in an autocrine or paracrine manner.
Subsequently, numerous systems have emerged.
The system we used in this study, the Rotary Wall Vessel (RWV) system, has been previously used to simulate the effects of a microgravity or RWV environment on numerous cell culture systems [ 13, 14].
It is therefore critical to understand, anticipate and quantify the effects of climate variability and climate change on numerous host plant/pathogen systems.
Environmental pollutants can adversely affect animal health and reproductive function, through either direct or indirect effects on numerous organs and systems.
But as I've argued in this space on numerous occasions, our system of government is broken.
