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Therapeutic approaches have traditionally been based on hypothetical pathways elucidated through in vivo research on rodents.
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Chemical profiles were based on types deducted from hypothetical pathways and could be an oversimplification of the chemical diversity contained by over 500 individual alkaloid structures known from the subfamily [ 45, 47].
Based on this, the authors formulated hypothetical pathways connecting the expected outcomes of the intervention (planning and supervision) to the inputs (contact classes and mentoring).
In order to understand how the programme worked, we will further build and refine these hypothetical pathways based on a review of literature and the study findings to arrive at context mechanism outcome configurations.
Alkaloid structures were scored to one of eighteen types proposed by Jin [ 45, 46] based on hypothetical biosynthetic pathways [ 51].
Of note, a number of reports were dedicated to discovery of network structures (modules, clusters, hypothetical pathways, and so on) that could characterize pathologic conditions [ 10, 14, 15].
Over 500 alkaloids have been described from various species and have been subdivided into 18 major types based on hypothetical biosynthetic pathways [ 45- 47].
We propose hereafter 3 hypothetical pathways through which green spaces may have a beneficial effect on pregnancy outcomes.
These results are discussed using a conceptual framework with 3 hypothetical pathways by which green spaces may have a beneficial effect on adverse pregnancy outcomes: (i) a psychological pathway, (ii) a physiological disruption process and (iii) an environmental pathway.
Our manuscript addresses two hypothetical pathways for ladderane biosynthesis.
There are yet other hypothetical pathways not involving DNhpom.
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