The Australian VGII population has been in the spotlight since 2005, when it was suggested as the possible origin of an on-going outbreak of cryptococcosis at Vancouver Island, BC, Canada [16].
Secondly, the data have revealed evidence of a potential on-going outbreak throughout Australia due to a limited number of VGII genotypes, possibly caused by a founder effect followed by clonal expansion.
We propose novel 'adaptive' real-time vaccination strategies that may guide vaccine allocation based on the age patterns of morbidity and mortality of an on-going outbreak, and compare their effectiveness with that of strategies targeted towards traditional influenza high risk age groups, i.e., young children and seniors.
On the other hand, the study period coincided with a large, on-going outbreak of pertussis in NSW, which began in 2008 [ 14].
The on-going outbreak now spans five West African countries (Guinea, Liberia, Nigeria, Sierra Leone and Senegal) and was recently declared a Public Health Emergency of International Concern by the World Health Organization.
Furthermore, when the analysis was repeated without using data about the on-going outbreak, an area deemed to be at risk was still within 5 kilometres of the village thought to the origin of the current outbreak.
"We have a significant, serious outbreak going on here," said David A. Papi, director of the Middlesex County Public Health Department.
You have a bad acne outbreak right before going on a hot date, even though you haven't had a pimple in weeks.
"Even if it were H5N1, we would still be looking for clear evidence of widespread community outbreaks going on in countries in multiple regions," said Fukuda.
"It is very important that we look at that resource because this outbreak was identified because of a lot of work going on around preparedness".
