However, excessive or chronic glial activation and/or failure to resolve the neuroinflammatory response can become damaging and can exacerbate on-going disease processes, including those relating to PD (Rogers et al., 2007; McGeer and McGeer, 2008; Barres, 2008).
The system also has potential to be used for automated on-going disease surveillance.
The presense of leprosy among children is an indicator of on-going disease transmission in the community.
Non-adherent patients may be involved in on-going disease transmission and are at increased risk of treatment failure and developing drug-resistant disease [ 5, 17- 19].
Such sites occur in embryonic development but also at vascular loci in the adult that are vulnerable to disease or directly involved in on-going disease.
Restriction of the analyses to persons who survived long enough to attain a given educational level, in order to investigate a possible effect of on-going disease, also showed no difference in educational pattern from that of all survivors.
Eight infected individuals were selected from a panel of naturally M. bovis-infected animals maintained for on-going disease surveillance at the Irish Department of Agriculture, Fisheries and Food, Backweston Laboratory Campus (Celbridge, Co. Kildare, Ireland).
In the context of the results reported here, while the MHC allelic richness is at times low, in the absence of any data or evidence of on-going disease challenge it would be speculative to attempt to draw any conclusions.
No-one went on to develop the disease and there were no severe side-effects to the treatment.
By doing that in large numbers, researchers can understand with more precision what is going on in disease states.
As the research going on, more diseases would be reported to associate with these low tissue specific miRNAs.
