Based on functional classifications of these genes, SLIT3 is the strongest functional candidate due to its role in axon development.
Using ClueGO (v2.1.3) plugin, [ 79] we performed an enrichment analysis based on functional classifications available at Kyoto Encyclopedia of Genes and Genomes (KEGG) [ 80], Reactome [ 81] and Gene Ontology (GO) [ 82], using the complete set of probes of 32 K cDNA microarray as reference.
Knowledge based computational techniques for function prediction rely on functional classification schemes [ 12] such as Functional Catalogue (FunCat) [ 13], Clusters of Orthologous Groups (COGs) [ 14], and Gene Ontology (GO) [ 15], among which GO is the most commonly used annotation system.
Notably, the global analysis of the C. cacaofunesta mitochondrial function that was based on functional classification (GO) of the experimentally identified proteins reflects the functional grouping of the full set of predicted mitochondrial proteins.
Next, functional assignment was done for 29,624 rice FST genes based on functional classification information from the MapMan Toolkit.
Base on functional classification, binding dependence and structural location of RPLs, a hierarchical model has been proposed for 60S assembly with assembly beginning at the solvent side (Gamalinda et al., 2014).
a Relative abundance of direct 454 sequences and fosmid metagenomic library Illumina sequences at the phylum level, and b based on functional classification as compared to the SEED database (Overbeek et al. 2005).
Based on functional classification, genes affected by age and/or diet were involved in cellular development, nutrient metabolism, and signal transduction.
Paralogs were identified in a number of prokaryotes, and these paralogs were compared to singletons of persistent orthologs based on functional classification.
Functional categories of these probe sets based on MIPS (Munich Information Center for Protein sequences) are shown in Figure 3. Furthermore, we compared the common probe sets between heat stress and recovery, and analyzed probe sets unique to both treatments, based on functional classification.
We compared the distribution of Xl-PSID intensity values for the four gene categories in order to ascertain potential differences in the relative expression levels of inner ear genes based on functional classification.
