Your English writing platform
Discover LudwigExact(5)
Both ERα and ERβ1 require ligand binding, and ERβ1 can form homodimers as well as ERα ERβ1 heterodimers on ERE.
Three separate experimental protocols were used to examine the effects of E2 and IL-1β on ERE activity in TERT-EEC.
As a result, although each of these replacements reduces binding affinity to every single RE, they do so most radically on ERE while only weakly affecting SREs.
In our current study, we did not find any effect of IL-1β on ERE activity in Ishikawa cells in the absence or presence of E2 at a 24 h time point.
This inhibition required a direct interaction between active ERα and BRCA1 (aa 338 379 of ERα) and their co-recruitment on ERE which blocked further ERα recognition by coactivators such as p300., Increasing concentrations of estrogen or overexpression of cyclin D1 which antagonizes and excludes BRCA1, induces estrogen responsive genes.
Similar(55)
Mr. Santos is a talker, and he often spent almost as long introducing a song as singing it, like on "Eres Mia," a saucy, almost rude number about maintaining control over a woman, even as she marries someone else.
These FAs also attenuated the effects of E2 under co-incubation conditions (Fig. 3.I.B). Figure 3.I shows the data for the effects of FAs on ERE-luciferase activity at a FAs concentration of 10−6 M and co-incubation with 10−9 M E2 (full data in Fig. S4).
As shown in Figure 1, 2.5 uM BTB treatment could not completely block E2-induced ER transactivation on ERE-luciferase.
Unlike the treatment effects on (ERE -luc ERE -lucon in all threxpressionnes, NFκB and AP-1 drinen reporters showed no treallenthreeponses in TAM-sensitive Mcellcelines
Depletion of MP1 in MCF-7 cells also resulted in decreased levels of ERα protein, mRNA (data not shown) and transcriptional activity on ERE-containing promoters.
Cells cultured on bFGF-tethered ERE-D20 were well attached on ERE-D20 and underwent proliferation without addition of soluble bFGF.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com