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The main objective of allele mining is to identify a small number of genomes and accessions from a large collection based on either sequence or phenotypic information.
It also gives equal weight to gaps on either sequence.
Although many efforts have been made in this regard, most of them were based on either sequence similarity or protein-protein interaction (PPI) information.
There was no significant difference in CNR on either sequence.
We then identified putative orthologs in 13 vertebrate genomes, based on either sequence similarity or local synteny conservation.
Despite catalyzing the same reaction they differ in substrate specificity and do not share any significant homology on either sequence or structural level.
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Various computational methods have been developed to infer the protein functions based on either the sequences or domains of proteins.
These studies suggest that the combination of sequence and structural information can improve prediction performance, compared to classifiers based on either sequences or structures.
were cleaned with Sephadex (Sigma) and sequenced on either an ABI 3730 or 3130xl capillary sequencer.
The datasets analyzed comprise crystal structures with non-redundant amino-acid sequences, based on either a 70% or a 30% sequence-identity threshold (21,780 and 13,735 structures, respectively).
Samples were sequenced on either an ABI 3100 or ABI 3700 automated DNA sequencer (Applied Biosystems, Foster City, CA, USA) at the Wadsworth Center Molecular Genetics Core facility.
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