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We then used these equations to quantify the effects of selection on effective size using parameters relevant to HIV-1 evolution in vivo.
All in all, the mortality between 1+ and 3+, although variable between sexes and seasons, does seem to be rather random among families, acting to reduce the negative effect of the strong skew in individual reproductive success on effective size and Nb /N ratios.
To evaluate the consequences of repeat spawning on effective size in brown trout, we introduced obligate mortality (semelparity) after a maturation event in the model.
A natural progression in this area of research is to develop inferences of census population sizes based on effective size estimates (Palstra and Ruzzante 2008) and how these could be used to assist management of natural resource species.
Overall, these results emphasize the dynamic impacts of both natural processes and hatchery rearing on effective size, the significance of multigenerational monitoring, and the need to understand the factors influencing the success of supportive breeding programs as a whole.
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As noted in previous assessments, precision of the estimate depends on the magnitude of effective size itself, with greater precision achieved for small populations.
We used simulated data to assess the influences of overlapping generations on the estimates of effective size provided by the linkage disequilibrium (LD) method.
Values of effective size based on linkage disequilibrium were generally larger in magnitude than those based on temporal-method estimators.
Based on two alternative assumptions on the effective size, we used two alternative models to estimate the average fitness cost of the S alleles (fig. 1).
This process of elimination, which correlates directly with infertility, will, obviously, be greatly dependant on the inbreeding coefficient, i.e. on the effective size of the population.
We will compare the results of these two meta-analyses, and then make a decision on whether the lower quality studies will be excluded on the basis of sample size, strength of evidence and influence on pooled effective size.
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