MPA could exert direct intracellular effects on division rates of breast ductal epithelial cells in a manner that achieves a high cell division rate regardless of the other sex hormone concentrations.
It is, however, necessary to interpret these data carefully because the distance from the root tip to the lowest position of the Casparian band depends on cell division rate, cell elongation rate as well as the time required for formation of the band in individual cells.
The mean proportion of GFP-tagged blastomeres was similar to untagged blastomeres in both groups of embryos at the 16- and 32-cell stages (Table 3), indicating that expression of these aPKCλ constructs had no effect on cell division rate.
Depending on the concentration, auxin acts in different fashions on the cell division rate: low and high auxin concentrations have a negative effect, whereas its intermediate concentrations has a positive effect [ 28], thereby making the curve of dose dependence bell-shaped.
To measure the effect of TGFβ2 on the symmetric division rate of the LTP/STP cancer cells, the treatment was performed by adding 100 ng/ml of TGFβ2 to growth medium at every passage for 4 passages.
These models rely on hypotheses on division control: the division rate of a cell, i.e. the instantaneous probability of its dividing, can be assumed to depend either on cell age (i.e. the time elapsed since birth) or cell size.
Assuming that there is no cellular sliding, the auxin effect on meristematic cell size might not only depend on cellular expansion, but also on altered division rates.
The stability of the knockdown depends mostly on the stability of the protein but also on factors like cell division rate or the degradation rate of the used siRNA.
In the classical 'sizer' model, the division rate depends on size and not on age whereas in the 'timer' model it depends on age and not on size.
The key assumption in this intuitive explanation is that if one nutrient is growth-limiting, then cell division rate depends linearly on the cell's ability to utilize this nutrient.
