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Previous studies showed that well-designed and carefully-controlled sera peptidomics can separate specific cancer-bearing patients and non-cancer controls based on distinctive patterns of signature peptides in the serum [10], [11].
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This theory and its predictions have recently been extended to genes with caste-limited expression in social insects (Linksvayer and Wade 2009) allowing one to distinguish adaptations based on what H. Robinson has called 'we genes' from those founded on 'me genes' in terms of distinctive patterns of sequence polymorphism and divergence.
Peritoneal/retroperitoneal metastases of distinctive pattern occurred in ILC.
In particular, we studied the grouping of genes known to be associated with neurobiological processes, excluding carbohydrate metabolism, based on their distinctive patterns within group.
Because phytoestrogens have significantly different affinities for ER-α and ER-β, the net effect of exposure to a particular phytoestrogen may depend on the distinctive patterns of ER-α and ER-β expression in different cell types (McDonnell 2004).
We found that the four sets of sequences fell consistently into two groups based on BLAST scores, distinctive patterns of conserved covariant amino acid residues [4] and, in the case of NifD, different patterns of invariant residues in the sequences flanking the Cys-α275 and His-α442 (Azobacter vinelandii sequence numbering) residues that attach the FeMo cofactor to NifD [5].
This raises the likelihood of finding distinctive patterns based on chance rather than on biology, a phenomenon called overfitting (Fehrmann et al, 2007).
Though one could argue that robbery and sexual assault had no such distinctive patterns, with peaks on Tuesday and Saturday (robbery) and Tuesday/Wednesday and Saturday (sexual assault), this could mean that robbers and sexual offenders are on the prowl on these particular day; alternatively, two types of robbers and sexual offenders could have distinctive temporal patterns.
According to the studies comparing the networks acquired from fMRI and PET, each DMN from these modalities shared quite the similar anatomical regions, although distinctive patterns were found on these two modalities (Di et al., 2012; Wehrl et al., 2013).
As expected, however, several of these studies have also illustrated that oxLDL generated in vivo is heterogeneous with distinctive patterns of modification on lipid and protein moieties, implicating the potential that oxLDL with antigenicity to a specific monoclonal antibody does not necessarily bind to and elicit biological actions via LOX-1.
241 Another interesting strategy for PPI inhibition is the use of transition metal complexes to target distinctive patterns of histidine residues on the surface of a protein.
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