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Doxazosin has a neutral effect on both peripheral and hepatic insulin action, but improves endothelium-dependent vasodilation.
Visceral hypersensitivity is demonstrated in 50 80% of patients with IBS and the origin of this phenomenon is probably based on both peripheral and central nervous system (CNS) mechanisms [1], [4].
The karyotype obtained on both peripheral blood lymphocytes and cultured fibroblasts (n = 134) was 46, XX.
Neural sensitisation is thought to arise in response to the actions of mediators on both peripheral and central nociceptive neurons.
For three patients, CXCR4 expression was evaluated on both peripheral and BM samples and no difference in expression was observed (data not shown).
They started by demonstrating that Piezo1 is expressed on both peripheral mature red blood cells and on pro-red blood cells developing in bone marrow in mice.
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At day 14, many cells appeared on the struts of both peripheral and central areas.
Based on the results, both peripheral vessel and new vessel formation were significantly increased by the BMP-2/S-NP/G treatment, along with the bridged defects at as early as 2 weeks, the healed defects at 8 weeks and the reunion of bone marrow cavity at 12 weeks.
The NO changes observed in our rat model were dependent on iNOS activity in both peripheral and central compartments.
Most of the studies on the effects of sugars on health and disease, at both peripheral and central levels, have been performed in rodents, and studies are missing in humans or other animal models closer to humans, such as the pig model.
In this chapter, we aim at providing an up-to-date review on nerve tissue engineering, focusing on both the peripheral and the central nervous systems (PNS and CNS, respectively).
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