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(C ) SMα protein expression is reduced on arteries from Notch3-deficient hearts.
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Experiments were performed separately on control arteries and on arteries derived from rats pretreated with low-dose aspirin (2 mg/kg) or high-dose aspirin (10 mg/kg).
In vitro experiments on the effect of contrast media on arteries obtained from different animal species showed different responses with respect to contraction/dilatation depending on the type of vessels and animal species; in these studies the contrast medium was not applied intraluminally [ 28].
The majority of in vitro experiments carried out to study the effect of contrast media on arteries obtained from different animal species showed differing responses with respect to contraction/dilation depending on the type of vessel and species being studied [ 8].
Modified from Jansen-Olesen et al. [48] Table 1 Data on relaxant responses induced by PACAP1 38, PACAP1 27 and VIP performed in vitro on cerebral arteries from different species Species PACAP1 38 PACAP1–27 VIP Reference pD2 Emax n pD2 Emax n pD2 Emax n Cat 7.9 ± 0.2 24 ± 9 7 7.7 ± 0.4 31 ± 5 7 8.3 ± 0.1 68 ± 8 8 Jansen-Olesen et al. 1994 [46] Rabbit n.d.
A myograph setup was used to test the vasodilator properties of the substances acetylcholine (ACh), sodium nitroprusside (SNP), sildenafil, prostaglandin E2 (pituitarytuitadenylatelate cyclase activating peptide-38 (PACAP-38), calcitonin gene-related peptide (CGRP) and NaCl buffer on meningeal arteries from human and rat.
We have recently investigated the vasoactive effects of several substances on cerebral arteries from human and rat in vitro in order to find common denominators that would allow us to understand more about the possible factors behind the migraine-associated symptoms [20].
Since our experiments were performed in rings with intact endothelium, we cannot exclude that the enhanced relaxant effect of these anaesthetics on pulmonary arteries from CH rats may be endothelium-mediated.
So what's kept me from a full-on, artery-clogging, saturated-fat-collecting, McDonald's hash brown binge?
Objective: To study the effect of 17β-estradiol on isolated omental arteries from preeclamptic women.
The relaxant effect of PACAP has been studied on isolated cerebral arteries from several species including humans.
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