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Univariable descriptive analysis was performed on all explanatory variables.
As this procedure uses only those individuals who have complete information on all explanatory variables results were validated in unified regression models.
Details on all explanatory variables, including definitions, measurement, and reliability, is presented in Additional file 2. Bold statistically significant (p <.05).
Of the 194 children and families participating when the child was 6 years of age, 174 had complete information on all explanatory variables and are included in the results described below.
The subset included in the present analysis was composed of 215 of these mother child pairs who also had available data on all explanatory or potential confounding variables of interest.
The subset included in the present primary analysis was composed of 198 of these mother child pairs who also had available data on all explanatory or potential confounding variables of interest as well as postnatal BPA measurements in the child at age 3 years.
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We therefore included patients in the final multilevel models only if they had complete data on all the explanatory variables.
In the analysis of related factors, the series was restricted to the period 1996 2006, since this was the period for which data on all the explanatory variables were available.
We then added individual covariates before including area-level remoteness and neighborhood disadvantage (separately or simultaneously) with the full model being simultaneously adjusted for all explanatory variables on both levels.
On the global model, all explanatory variables listed in Table 1 were used and finally the optimum model is presented from the global model in which very few independent variables having collinearity problems were omitted (Table 4), by calculating the variance inflation factors (VIFs), where (VIFs <5) implies absence of collinearity.
We performed Shapiro tests on all our explanatory variables, and because all of them were normally distributed, we used a normal error distribution in our models (results of the Shapiro tests: average larval mass W = 0.97, P = 0.22; brood size W = 0.97, P = 0.17; P = 0.46, female lifespan W = 0.96, P = 0.07; male lifespan W = 0.97, P = 0.14).
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