PH is classified as episodic paroxysmal hemicrania (EPH) or chronic paroxysmal hemicrania (CPH) depending on the presence of a remission period.
In fact, lifting weights just twice a week led to a remission rate that was on par with antidepressants.
Our review, using a fixed time analysis, suggests a smaller difference between the groups with a higher probability of maintaining a remission on antibiotics (1 study; RR 1.28, 95% CI 0.94 to 1.76) although this was not statistically significant.
As an alternative approach to the cluster analysis approach, a remission analysis based on the Andreasen remission criteria was performed [ 5].
Therefore, sequential PCT following remission on A-CT may be a good alternative or addition to TAU.
However, recent meta-analysis showed that after remission on A-CT, many responders still have a relapse-recurrence (29 % within 1 year and 54 % within 2 years) [ 8].
Therefore, the (cost-) effectiveness of PCT after remission on A-CT is still unknown and the main goal of this study.
On-drug remission is now an important and realistic therapeutic goal, which is increasingly reflected in the design of clinical trials for RA.
As time-to-remission was calculated in months, this means that patients who achieved first remission one month earlier, had a higher chance on sustained remission, an OR of 1.11 than patients who achieved first remission one month later.
In addition, patients with higher baseline depressive severity had a greater likelihood of achieving remission on all remission outcomes.
