Electron microscopy reconstruction showed how TnI binding to both actin and tropomyosin at low Ca2+ competes with tropomyosin for a common site on actin and drives tropomyosin movement to a constrained, relaxing position to inhibit myosin crossbridge association.
The corepressors, Mth1 and Std1, play partially redundant roles in regulation: they each bind to a common site on Rgt1 to suppress transcriptional activation and block access to PKA, whose hyperphosphorylation of Rgt1 elicits its eviction from promoters (Palomino et al. 2006).
FRANKFURT — There was a touch of gloating in the most recent earnings report issued by Kuka, a company based in the Bavarian city of Augsburg whose orange industrial robots are a common site on auto assembly lines around the world.
The two-seat Smart car is a common site on urban streets in Europe but has been a perennial money loser for Daimler since its introduction more than a decade ago.
As the walls are being torn down around them, they are the "last-standers", a common site on Chinese demolition sites as a few die-hard residents hold on.
EZH2 is located on chr7q36.1, which is not a common site of chromosomal gain in NPC.
Therefore, the Ser1928 on the α1c subunit is a common site for LTCC phosphorylation by PKA, PKC, and PKG.
Despite the structural variability, all Opa proteins target a common site on the receptors whose centre of binding appears to be Ile-91 on the CFG face of the N-domains.
Delay eyeblink conditioning depends on plasticity in the cerebellum, a common site of anatomical deviation in patients with autism, and cerebellar gross and cellular malformation are common features of autistic brains (Wang et al., 2014).
The CHK2 kinase, the human homologue of yeast RAD53, is located on chromosome 22q which is a common site for LOH in vulval cancer (Worsham et al, 1991; Pinto et al, 1999).
