A clue to this problem may come from differences in substrate- versus ubiquitin-recognition: The SCFCdc4 catalyses poly-ubiquitin K48-specific chain assembly in a highly processive reaction that depends on the presence of an acidic loop within Cdc34 and on a hydrophobic patch in ubiquitin adjacent to the K48-acceptor site (Petroski and Deshaies, 2005).
The pH of fresh ash leachates is highly variable, depending on the presence of an acidic gas condensate (primarily as a consequence of the gases SO2, HCl and HF in the eruption plume) on the ash surface.
These observations imply that the main principle of CARD-CARD interactions is based on the engagement of an acidic patch built of helices 1 and 4, with a basic patch composed of helices 2 and 3.
The presence of an acidic hydrogen on the surfactant in Cloisite 93A appears to play a strong role in its 'CO2-philicity'.
The promoting effect of an acidic support on the hydrodesulfurization (HDS) of 4,6-dimethyldibenzothiophene (DMDBT) was studied by comparing the activity and selectivity of Pt/HZSM-5 with those of Pt/γ-Al2O3 and Pt/SBA-15.
These results demonstrate that negatively charged residues, but not positively charged ones, surrounding a non-polar patch on an acidic protein can completely reverse the decrease in its solubility caused by the patch of non-polar surface residues.
Journalists who presumed to ask what Bill Murray's character whispers in her ear at the end of the film could bank on an acidic dismissal: "Oh, you think you're the first one to ask?" she replied to one reporter.
25 Specifically, two key enzymes, β-glucocerebrosidase and acid sphingomyelinase, which metabolize spingomyelin and glucosylceramide to ceramide, require on an acidic pH for optimal enzymatic activity.
Between the trios Mr. Peled and Mr. Goldstein collaborated on an acidic account of Shostakovich's Cello Sonata (Op. 40), and Mr. Goldstein offered colorful readings of Schubert's appealing but slight Six German Dances (D. 820) and Ginastera's characterful "Danzas Argentinas" (Op. 2).
who used a novel Ni catalyst supported on an acidic zeolite, HBeta.
