First, although we omitted studies investigating the effect of high-carbohydrate diets that were also high in dietary fiber, it is possible that the additional phytochemicals (including fiber itself), which are inevitably accompanied by a substantial amount of carbohydrate, influence the metabolic effects regardless of the change in C/F ratio.
In most of these omitted studies, the BMI range associated with the lowest mortality was around 22.5 25, particularly after accounting for smoking status and reverse causation due to prevalent diseases (Tobias & Hu, 2013).
However, the further hand search of references reduces possibly omitted studies.
Where performance is consistently adequate across all combinations of the omitted study, a final step can be to utilise the IPD from all studies to produce the final specification of the model.
If relevant, the results of the methodological quality assessment will be used to perform sensitivity analyses to test the effect of omitting studies at high risk of bias.
In future updates, we will carry out sensitivity analysis to explore the effects of trial quality assessed by allocation concealment and other risk of bias components, by omitting studies rated as 'high risk of bias' for these components.
We also examined the effect of omitting studies with nested case-control design.
We performed a sensitivity analysis to: (1) investigate the effect of the model assumed on the overall effect size, by running the analysis under the random effects model and observing if a difference exists (2) explore the effect of the study quality on the summary effect estimate, by omitting studies rated as "high risk of bias" for both random sequence generation and allocation concealment.
Species inhabiting other canopy microhabitats have previously been considered to represent a minor component of insect biodiversity and have subsequently been overlooked or omitted in studies of insect biodiversity (see - ).
A statistically nonsignificant reduction in the risk of non-Hodgkin lymphoma was observed in statin users omitting the studies of Fortuny et al.
