Originally, they only intended to measure how olfactory tubercle cells in mice responded to smell.
In fact, the olfactory tubercle is physiologically well-placed to receive both smell and sound information from the outside world; and so Wesson and Wilson broadened their investigation.
Two New York researchers, Daniel Wesson and Donald Wilson, were confronted with this fact when they began investigating an "enigmatic" area of the brain known as the olfactory tubercle.
The patent says the stem cells can be taken from parts of the central nervous system like the brain cortex, olfactory tubercle, retina, the hippocampus, thalamus or hypothalamus, and the brain stem, cerebellum and spinal cord.
All dopamine receptor knockout mice examined exhibited increased A2A receptor binding in the caudate putamen, nucleus accumbens and olfactory tubercle.
Dopamine D1 receptor binding was decreased in the caudate putamen, nucleus accumbens, olfactory tubercle and ventral pallidum of D2 receptor knockout mice.
Within the ventral striatum, immunoreactivity was more pronounced within the olfactory tubercle and the shell region of the nucleus accumbens than in the nucleus accumbens core and was especially marked within the lateral striatal stripe.
Strong β-galactosidase staining was found predominantly in the CP, NAc and olfactory tubercle.
OlfA likely includes the olfactory tubercle and other small portions of primary olfactory cortex.
One of the groups received vehicle injections into the medial olfactory tubercle throughout the experiment.
Amphetamine injections into the lateral olfactory tubercle reliably increased activity, but not lever pressing.
