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Here, taking advantage of the possibility to unequivocally identify V1r orthologs in teleosts, we analyzed the olfactory expression and evolutionary constraints of a pair of clustered fish V1r receptor genes, V1r1 and V1r2.
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Four genes, none of which encode an OR gene, were found to be expressed more strongly in female olfactory epithelium (expression levels 1.7 times higher; Table 2).
Thus, all 48 ORs that showed olfactory epithelial expression in our analysis were also highly expressed in the results of Zhang et al. (see Additional file 6, p = 0.0001, chi-square test = 21).
Monahan, K. et al. Cooperative interactions enable singular olfactory receptor expression in mouse olfactory neurons.
Magklara, A. et al. An epigenetic signature for monoallelic olfactory receptor expression.
Markenscoff-Papadimitriou, E. et al. Enhancer interaction networks as a means for singular olfactory receptor expression.
Recent literature suggest that olfactory receptor expression is highly variant in the human population and that this may explain the functional variation in taste and olfaction that has been observed for decades.
We use spPCR to 1) map a GAL4 enhancer trap located inside a natural transposon, pinpointing a master regulatory region for olfactory neuron expression in the brain; and 2) map all commonly used centromeric FRT insertion sites.
Figure 4 summarises sex differences in olfactory gene expression.
It has been shown however that olfactory gene expression fluctuates across the circadian cycle [ 37].
Because histones are central components of chromatin, we suspected that loss of H2be might affect olfactory gene expression.
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CEO of Professional Science Editing for Scientists @ prosciediting.com