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Can the olfactory cells be cultivated from the patients themselves, as a way around the debate over stem cells?
Humans have about five million olfactory cells, while dogs have as many as two hundred and twenty million.
Kristensson K, Olsson Y. Uptake of exogenous proteins in mouse olfactory cells.
In addition, extracellular recordings from the coupled olfactory cells demonstrate that microelectrodes can efficiently monitor the membrane potential changes originated from olfactory cells in response to odorant stimulations.
The molecules start a process by which olfactory cells send messages to the olfactory bulb, a part of the brain that is associated with smell.
ONB arise from the neuroepithelial olfactory cells involving the cribriform plate of the ethmoid.
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Rare accompanying malignancies, such as cancers of duodenal, gallbladder, tongue, soft palate, nasal olfactory cell, and osteosarcoma, were also identified.
Therefore, it is becoming evident that non-olfactory cells can hijack ORs as a general signaling pathway to achieve other cell-specific functions.
Barnett, S. C. Olfactory ensheathing cells: unique glial cell types?
Macedo-Ramos, H. et al. Olfactory ensheathing cells as putative host cells for Streptococcus pneumoniae: Evidence of bacterial invasion via mannose receptor-mediated endocytosis.
Olfactory receptor cells are continually replaced, with new cells developing from basal cells in the olfactory epithelium.
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