Abnormal CAG repeats in the mildly affected group were slightly smaller than in the early group, but the latter were older at examination (Table 1).
Inclusion criteria required that the participant was aged 65 years or older at examination in 2011 or 2012, lived in Obu, and had not participated in another study.
One possible explanation is that there was some selection bias and those who were older at examination were not included in an earlier examination due to a perceived immaturity.
The men in our study were aged between 17 years and 25 years old at these examinations (mean age 18.3 years); 92% were 17 years or 18 years of age.
Eligible participants for this analysis were women who were 50 years or older at baseline examination.
We included studies with participants aged 50 years and older at baseline examination in which the authors purport to have measured frailty.
The participants that developed HF were older at baseline examination and more likely to have diabetes, higher systolic and diastolic blood pressure, be inactive, to live alone, have lower education, be alcohol abstainers, and score higher on the HADS-D subscale.
Cumulative incidence of diabetes, i.e. the 10-year risk of developing diabetes, was estimated using the panel dataset composed of people who were 30, 40, and 50 years old at their first health examination and were invited for a re-examination 10 years later.
Affected boys were at least 6 months' old at time of medical examination.
Students who were more than 30 years old at the time of examination were excluded (n = 482) leaving 11,274 participants.
