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Simple ointment base was prepared according to the British Pharmacopoeia [ 24] using hard paraffin, cetostearyl alcohol, white soft paraffin and wool fat.
The 10% (w/w) LJEE ointment was composed of 10 g of LJEE incorporated into 100 g of a simple ointment base.
The ointment base of Chloromycetin consists of a mixture of soft white paraffin, liquid paraffin, and plastibase 30W, which is a plasticised hydrocarbon gel consisting of 95% mineral oil and 5% polyethylene glycol.
Our placebo ointment consisted of 50% soft white paraffin and 50% liquid paraffin and was not completely identical to the ointment base of Chloromycetin as it did not contain plastibase 30W.
aagainst control; p < 0.05, p < 0.001 The mean tensile strength in the group treated with simple ointment base BP tended to increase by about 19.4 % compared to untreated controls, which failed to reach statistical significance.
Healing was assessed by the rate of wound contraction in skin wound sites in rats treated with simple ointment base, 10% (w/w) LJEE ointment, or the reference standard drug, 0.2% (w/w) nitrofurazone ointment.
Similar(52)
Further certain traditional emollients in lotion or ointment bases are often in formulations that patients will rarely use consistently.
An ointment or cream based on sulforaphane could reduce the risk of skin cancer from UV radiation, Talalay says; it would not replace traditional sunscreen--which blocks UV rays--but would help cells handle any damage.
An ointment formulation is usually better tolerated than a cream base.
Application of mupirocin ointment in paraffin base every eight hours for five days.
Only use A and D ointment and zinc oxide based ointments (be careful even with brand-name products) if there is diaper rash.
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